3KNA
M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA
Summary for 3KNA
Entry DOI | 10.2210/pdb3kna/pdb |
Related | 1U09 1WNE 2D7S 2E9T 2E9Z 2F8E 3KLV 3KMQ 3KMS 3KOA |
Descriptor | 3D polymerase, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*C)-3'), ... (5 entities in total) |
Functional Keywords | rna dependent rna polymerase, 3d polymerase, foot-and-mouth disease virus, ribavirin, transferase-rna complex, transferase/rna |
Biological source | Foot-and-mouth disease virus - type C |
Total number of polymer chains | 3 |
Total formula weight | 57290.34 |
Authors | Ferrer-Orta, C.,Verdaguer, N.,Perez-Luque, R. (deposition date: 2009-11-12, release date: 2010-07-07, Last modification date: 2023-11-01) |
Primary citation | Ferrer-Orta, C.,Sierra, M.,Agudo, R.,de la Higuera, I.,Arias, A.,Perez-Luque, R.,Escarmis, C.,Domingo, E.,Verdaguer, N. Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin J.Virol., 84:6188-6199, 2010 Cited by PubMed: 20392853DOI: 10.1128/JVI.02420-09 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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