3KKV

Structure of PKA with a protein Kinase B-selective inhibitor.

3KKV の概要

• エントリーDOI: 10.2210/pdb3kkv/pdb
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, PKI kinase inhibitor, (2S)-1-{[6-furan-3-yl-5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxy}-3-(1H-indol-3-yl)propan-2-amine, ... (4 entities in total)
• 機能のキーワード: protein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Bos taurus (bovine); 詳細
• 細胞内の位置: Cytoplasm : P00517
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43476.34

構造登録者

Elkins, P.A.,Concha, N.O. (登録日: 2009-11-06, 公開日: 2010-12-22, 最終更新日: 2024-10-09)

• 主引用文献: Lin, H.,Elkins, P.A.,Concha, N.O.,Heerding, D.,Wang, W.,Nidarmarthy, S.,Luengo, J.I.,Nelson, R.,Knick, V.B.,Choudhry, A.E.; Structure of PKA with a protein Kinase B-selective inhibitor.; To be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)