3KJ6

Crystal structure of a Methylated beta2 Adrenergic Receptor-Fab complex

Summary for 3KJ6

• Entry DOI: 10.2210/pdb3kj6/pdb
• Descriptor: Beta-2 adrenergic receptor, Fab light chain, Fab heavy chain, ... (4 entities in total)
• Functional Keywords: transmembrane helices, cell membrane, disulfide bond, g-protein coupled receptor, glycoprotein, lipoprotein, membrane, palmitate, phosphoprotein, polymorphism, receptor, transducer, transmembrane, signaling protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane ; Multi- pass membrane protein : P07550
• Total number of polymer chains: 3
• Total formula weight: 88604.47

Authors

Bokoch, M.P.,Zou, Y.,Rasmussen, S.G.F.,Liu, C.W.,Nygaard, R.,Rosenbaum, D.M.,Fung, J.J.,Choi, H.-J.,Thian, F.S.,Kobilka, T.S.,Puglisi, J.D.,Weis, W.I.,Pardo, L.,Prosser, S.,Mueller, L.,Kobilka, B.K. (deposition date: 2009-11-02, release date: 2010-02-16, Last modification date: 2021-10-13)

• Primary citation: Bokoch, M.P.,Zou, Y.,Rasmussen, S.G.,Liu, C.W.,Nygaard, R.,Rosenbaum, D.M.,Fung, J.J.,Choi, H.J.,Thian, F.S.,Kobilka, T.S.,Puglisi, J.D.,Weis, W.I.,Pardo, L.,Prosser, R.S.,Mueller, L.,Kobilka, B.K.; Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.; Nature, 463:108-112, 2010; PubMed: 20054398; DOI: 10.1038/nature08650

Experimental method

X-RAY DIFFRACTION (3.4 Å)