3KJ6

Crystal structure of a Methylated beta2 Adrenergic Receptor-Fab complex

3KJ6 の概要

• エントリーDOI: 10.2210/pdb3kj6/pdb
• 分子名称: Beta-2 adrenergic receptor, Fab light chain, Fab heavy chain, ... (4 entities in total)
• 機能のキーワード: transmembrane helices, cell membrane, disulfide bond, g-protein coupled receptor, glycoprotein, lipoprotein, membrane, palmitate, phosphoprotein, polymorphism, receptor, transducer, transmembrane, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cell membrane ; Multi- pass membrane protein : P07550
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 88604.47

構造登録者

Bokoch, M.P.,Zou, Y.,Rasmussen, S.G.F.,Liu, C.W.,Nygaard, R.,Rosenbaum, D.M.,Fung, J.J.,Choi, H.-J.,Thian, F.S.,Kobilka, T.S.,Puglisi, J.D.,Weis, W.I.,Pardo, L.,Prosser, S.,Mueller, L.,Kobilka, B.K. (登録日: 2009-11-02, 公開日: 2010-02-16, 最終更新日: 2021-10-13)

• 主引用文献: Bokoch, M.P.,Zou, Y.,Rasmussen, S.G.,Liu, C.W.,Nygaard, R.,Rosenbaum, D.M.,Fung, J.J.,Choi, H.J.,Thian, F.S.,Kobilka, T.S.,Puglisi, J.D.,Weis, W.I.,Pardo, L.,Prosser, R.S.,Mueller, L.,Kobilka, B.K.; Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.; Nature, 463:108-112, 2010; PubMed: 20054398; DOI: 10.1038/nature08650

実験手法

X-RAY DIFFRACTION (3.4 Å)