3KIO

mouse RNase H2 complex

3KIO の概要

• エントリーDOI: 10.2210/pdb3kio/pdb
• 分子名称: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C, ... (4 entities in total)
• 機能のキーワード: ribonuclease, aicardi-goutieres syndrome, rnase h2, protein complex, autoimmune disease, endonuclease, hydrolase, metal-binding, nuclease, nucleus, phosphoprotein, acetylation
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Nucleus (By similarity): Q9CWY8 Q80ZV0 Q9CQ18
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 89509.58

構造登録者

Shaban, N.,Harvey, S.,Perrino, F.W.,Hollis, T. (登録日: 2009-11-02, 公開日: 2009-11-17, 最終更新日: 2011-07-13)

• 主引用文献: Shaban, N.M.,Harvey, S.,Perrino, F.W.,Hollis, T.; The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction.; J.Biol.Chem., 285:3617-3624, 2010; PubMed: 19923215; DOI: 10.1074/jbc.M109.059048

実験手法

X-RAY DIFFRACTION (2.9 Å)