3KH3

Crystal structure of human Cu/Zn superoxide dismutase recombinantly produced in Leishmania tarantolae; P212121 crystal form containing 12 chains in the asymmetric unit

3KH3 の概要

• エントリーDOI: 10.2210/pdb3kh3/pdb
• 関連するPDBエントリー: 3KH4
• 分子名称: Superoxide dismutase [Cu-Zn], COPPER (II) ION, ZINC ION, ... (4 entities in total)
• 機能のキーワード: eukaryotic expression, leishmania tarantolae, amyotrophic lateral sclerosis, antioxidant, disease mutation, disulfide bond, metal-binding, neurodegeneration, oxidoreductase, phosphoprotein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P00441
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 191766.38

構造登録者

Gazdag, E.M.,Blankenfeldt, W. (登録日: 2009-10-30, 公開日: 2010-08-11, 最終更新日: 2011-07-13)

• 主引用文献: Gazdag, E.M.,Cirstea, I.C.,Breitling, R.,Lukes, J.,Blankenfeldt, W.,Alexandrov, K.; Purification and crystallization of human Cu/Zn superoxide dismutase recombinantly produced in the protozoan Leishmania tarentolae.; Acta Crystallogr.,Sect.F, 66:871-877, 2010; PubMed: 20693657; DOI: 10.1107/S1744309110019330

実験手法

X-RAY DIFFRACTION (3.5 Å)