3KFM

Crystal Structure of the GluA4 Ligand-Binding domain L651V mutant in complex with kainate

Summary for 3KFM

Entry DOI	10.2210/pdb3kfm/pdb
Related	3KEI
Descriptor	Glutamate receptor 4, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE (3 entities in total)
Functional Keywords	glua4, ampa receptor, ligand-gated ion channel, ligand-binding domain, l651v, kainate, alternative splicing, cell junction, cell membrane, glycoprotein, ion transport, ionic channel, lipoprotein, membrane, palmitate, postsynaptic cell membrane, receptor, synapse, transmembrane, transport, transport protein
Biological source	Rattus norvegicus (brown rat,rat,rats) More
Total number of polymer chains	1
Total formula weight	28936.40
Authors	Gill, A.,Madden, D.R. (deposition date: 2009-10-27, release date: 2010-02-09, Last modification date: 2023-09-06)
Primary citation	Birdsey-Benson, A.,Gill, A.,Henderson, L.P.,Madden, D.R. Enhanced efficacy without further cleft closure: reevaluating twist as a source of agonist efficacy in AMPA receptors. J.Neurosci., 30:1463-1470, 2010 Cited by PubMed: 20107073 DOI: 10.1523/JNEUROSCI.4558-09.2010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation