3KFM

Crystal Structure of the GluA4 Ligand-Binding domain L651V mutant in complex with kainate

3KFM の概要

• エントリーDOI: 10.2210/pdb3kfm/pdb
• 関連するPDBエントリー: 3KEI
• 分子名称: Glutamate receptor 4, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE (3 entities in total)
• 機能のキーワード: glua4, ampa receptor, ligand-gated ion channel, ligand-binding domain, l651v, kainate, alternative splicing, cell junction, cell membrane, glycoprotein, ion transport, ionic channel, lipoprotein, membrane, palmitate, postsynaptic cell membrane, receptor, synapse, transmembrane, transport, transport protein
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28936.40

構造登録者

Gill, A.,Madden, D.R. (登録日: 2009-10-27, 公開日: 2010-02-09, 最終更新日: 2023-09-06)

• 主引用文献: Birdsey-Benson, A.,Gill, A.,Henderson, L.P.,Madden, D.R.; Enhanced efficacy without further cleft closure: reevaluating twist as a source of agonist efficacy in AMPA receptors.; J.Neurosci., 30:1463-1470, 2010; PubMed: 20107073; DOI: 10.1523/JNEUROSCI.4558-09.2010

実験手法

X-RAY DIFFRACTION (2.2 Å)