3KF2

The HCV NS3/NS4A protease apo structure

Summary for 3KF2

Entry DOI	10.2210/pdb3kf2/pdb
Related	3KEE
Descriptor	Polyprotein, 19-mer peptide from Genome polyprotein, ZINC ION, ... (4 entities in total)
Functional Keywords	hcv, ns3, protease, apo, hydrolase
Biological source	Hepatitis C virus More
Total number of polymer chains	4
Total formula weight	47385.35
Authors	Lindberg, J.D.,Nystrom, S.,Cummings, M.D. (deposition date: 2009-10-27, release date: 2010-03-09, Last modification date: 2023-11-01)
Primary citation	Cummings, M.D.,Lindberg, J.D.,Lin, T.-I.,de Kock, H.,Lenz, O.,Lilja, E.,Fellander, S.,Baraznenok, V.,Nystrom, S.,Nilsson, M.,Vrang, L.,Edlund, M.,Rosenquist, A.,Samuelsson, B.,Raboisson, P.,Simmen, K. Induced-Fit Binding of the Macrocyclic Noncovalent Inhibitor TMC435 to its HCV NS3/NS4A Protease Target Angew.Chem.Int.Ed.Engl., 49:1652-1655, 2010 Cited by PubMed: 20166108 DOI: 10.1002/anie.200906696 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation