3K9F

Detailed structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases

3K9F の概要

• エントリーDOI: 10.2210/pdb3k9f/pdb
• 関連するPDBエントリー: 2NOV 3FOE 3FOF
• 分子名称: DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, DNA (5'-D(*AP*CP*CP*AP*AP*GP*GP*T*CP*AP*TP*GP*AP*AP*T)-3'), ... (9 entities in total)
• 機能のキーワード: quinolone, topoisomerase, dna, protein-dna cleavage complex, streptococcus pneumoniae, levofloxacin, cell membrane, dna-binding, isomerase, membrane, atp-binding, nucleotide-binding, isomerase-dna complex, isomerase/dna
• 由来する生物種: Streptococcus pneumoniae; 詳細
• 細胞内の位置: Cell membrane; Peripheral membrane protein (By similarity): P72525
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 195339.21

構造登録者

Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,Fisher, L.M.,Sanderson, M.R. (登録日: 2009-10-15, 公開日: 2009-10-27, 最終更新日: 2023-11-01)

• 主引用文献: Laponogov, I.,Pan, X.-S.,Veselkov, D.A.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R.; Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases; Plos One, 5:e11338-e11338, 2010; PubMed: 20596531; DOI: 10.1371/journal.pone.0011338

実験手法

X-RAY DIFFRACTION (2.9 Å)