3K8X

Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with tepraloxydim

3K8X の概要

• エントリーDOI: 10.2210/pdb3k8x/pdb
• 関連するPDBエントリー: 1OD2 1OD4 1UYR 1UYS 1UYT 1UYV
• 分子名称: Acetyl-CoA carboxylase, (5S)-2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-3-hydroxy-5-(tetrahydro-2H-pyran-4-yl)cyclohex-2-en-1-one (3 entities in total)
• 機能のキーワード: transferase, acetyl-coa carboxylase, carboxyltransferase, acc, ct, tepraloxydim, atp-binding, biotin, fatty acid biosynthesis, ligase, lipid synthesis, manganese, metal-binding, multifunctional enzyme, nucleotide-binding, phosphoprotein
• 由来する生物種: Saccharomyces cerevisiae (yeast)
• 細胞内の位置: Cytoplasm: Q00955
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 258657.87

構造登録者

Xiang, S.,Callaghan, M.M.,Watson, K.G.,Tong, L. (登録日: 2009-10-15, 公開日: 2009-12-01, 最終更新日: 2024-02-21)

• 主引用文献: Xiang, S.,Callaghan, M.M.,Watson, K.G.,Tong, L.; A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim.; Proc.Natl.Acad.Sci.USA, 106:20723-20727, 2009; PubMed: 19926852; DOI: 10.1073/pnas.0908431106

実験手法

X-RAY DIFFRACTION (2.3 Å)