3K7R

Crystal structure of [TM][CuAtx1]3

Summary for 3K7R

• Entry DOI: 10.2210/pdb3k7r/pdb
• Descriptor: Metal homeostasis factor ATX1, COPPER (II) ION, TETRATHIOMOLYBDATE, ... (5 entities in total)
• Functional Keywords: ferredoxin-like fold, protein-metal-drug complex, cu-mo metal cluster, chaperone, copper transport, ion transport, metal-binding, transport
• Biological source: Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast)
• Cellular location: Cytoplasm: P38636
• Total number of polymer chains: 12
• Total formula weight: 100973.51

Authors

Xue, Y.,Alvarez, H.M.,Robinson, C.D.,Mondragon, A.,O'Halloran, T.V. (deposition date: 2009-10-13, release date: 2009-11-24, Last modification date: 2023-09-06)

• Primary citation: Alvarez, H.M.,Xue, Y.,Robinson, C.D.,Canalizo-Hernandez, M.A.,Marvin, R.G.,Kelly, R.A.,Mondragon, A.,Penner-Hahn, J.E.,O'Halloran, T.V.; Tetrathiomolybdate inhibits copper trafficking proteins through metal cluster formation.; Science, 327:331-334, 2010; PubMed: 19965379; DOI: 10.1126/science.1179907

Experimental method

X-RAY DIFFRACTION (2.28 Å)