3K7R
Crystal structure of [TM][CuAtx1]3
Summary for 3K7R
Entry DOI | 10.2210/pdb3k7r/pdb |
Descriptor | Metal homeostasis factor ATX1, COPPER (II) ION, TETRATHIOMOLYBDATE, ... (5 entities in total) |
Functional Keywords | ferredoxin-like fold, protein-metal-drug complex, cu-mo metal cluster, chaperone, copper transport, ion transport, metal-binding, transport |
Biological source | Saccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast) |
Cellular location | Cytoplasm: P38636 |
Total number of polymer chains | 12 |
Total formula weight | 100973.51 |
Authors | Xue, Y.,Alvarez, H.M.,Robinson, C.D.,Mondragon, A.,O'Halloran, T.V. (deposition date: 2009-10-13, release date: 2009-11-24, Last modification date: 2023-09-06) |
Primary citation | Alvarez, H.M.,Xue, Y.,Robinson, C.D.,Canalizo-Hernandez, M.A.,Marvin, R.G.,Kelly, R.A.,Mondragon, A.,Penner-Hahn, J.E.,O'Halloran, T.V. Tetrathiomolybdate inhibits copper trafficking proteins through metal cluster formation. Science, 327:331-334, 2010 Cited by PubMed: 19965379DOI: 10.1126/science.1179907 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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