3K6B

X-ray crystal structure of the E2 domain of APL-1 from C. elegans, in complex with sucrose octasulfate (SOS)

Summary for 3K6B

Entry DOI	10.2210/pdb3k6b/pdb
Related	1RW6 3K66
Descriptor	Beta-amyloid-like protein, 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose (3 entities in total)
Functional Keywords	x-ray crystal structure, amyloid precursor protein, heparin binding, alternative splicing, amyloid, developmental protein, differentiation, glycoprotein, membrane, neurogenesis, transmembrane, cell adhesion
Biological source	Caenorhabditis elegans (nematode)
Total number of polymer chains	1
Total formula weight	29016.85
Authors	Hoopes, J.T.,Ha, Y. (deposition date: 2009-10-08, release date: 2009-11-10, Last modification date: 2023-09-06)
Primary citation	Hoopes, J.T.,Liu, X.,Xu, X.,Demeler, B.,Folta-Stogniew, E.,Li, C.,Ha, Y. Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site J.Biol.Chem., 285:2165-2173, 2010 Cited by PubMed: 19906646 DOI: 10.1074/jbc.M109.018432 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation