3K6B

X-ray crystal structure of the E2 domain of APL-1 from C. elegans, in complex with sucrose octasulfate (SOS)

3K6B の概要

• エントリーDOI: 10.2210/pdb3k6b/pdb
• 関連するPDBエントリー: 1RW6 3K66
• 分子名称: Beta-amyloid-like protein, 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose (3 entities in total)
• 機能のキーワード: x-ray crystal structure, amyloid precursor protein, heparin binding, alternative splicing, amyloid, developmental protein, differentiation, glycoprotein, membrane, neurogenesis, transmembrane, cell adhesion
• 由来する生物種: Caenorhabditis elegans (nematode)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29016.85

構造登録者

Hoopes, J.T.,Ha, Y. (登録日: 2009-10-08, 公開日: 2009-11-10, 最終更新日: 2023-09-06)

• 主引用文献: Hoopes, J.T.,Liu, X.,Xu, X.,Demeler, B.,Folta-Stogniew, E.,Li, C.,Ha, Y.; Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site; J.Biol.Chem., 285:2165-2173, 2010; PubMed: 19906646; DOI: 10.1074/jbc.M109.018432

実験手法

X-RAY DIFFRACTION (2.8 Å)