3JZF
Crystal structure of biotin carboxylase from E. Coli in complex with benzimidazoles series
Summary for 3JZF
Entry DOI | 10.2210/pdb3jzf/pdb |
Related | 3JZI |
Descriptor | Biotin carboxylase, CARBONATE ION, 2-[(2-chlorobenzyl)amino]-1-(cyclohexylmethyl)-1H-benzimidazole-5-carboxamide, ... (4 entities in total) |
Functional Keywords | biotin carboxylase, accc, acetyl coenzyme-a carboxylase, accase, atp-binding, biotin, fatty acid biosynthesis, ligase, lipid synthesis, nucleotide-binding |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 107471.04 |
Authors | Orth, P. (deposition date: 2009-09-23, release date: 2009-11-03, Last modification date: 2023-09-06) |
Primary citation | Cheng, C.C.,Shipps, G.W.,Yang, Z.,Sun, B.,Kawahata, N.,Soucy, K.A.,Soriano, A.,Orth, P.,Xiao, L.,Mann, P.,Black, T. Discovery and optimization of antibacterial AccC inhibitors. Bioorg.Med.Chem.Lett., 19:6507-6514, 2009 Cited by PubMed: 19875284DOI: 10.1016/j.bmcl.2009.10.057 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.13 Å) |
Structure validation
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