3JWD

Structure of HIV-1 gp120 with gp41-Interactive Region: Layered Architecture and Basis of Conformational Mobility

Summary for 3JWD

• Entry DOI: 10.2210/pdb3jwd/pdb
• Related: 3JWO
• Descriptor: HIV-1 GP120 ENVELOPE GLYCOPROTEIN, T-cell surface glycoprotein CD4, FAB 48D LIGHT CHAIN, ... (7 entities in total)
• Functional Keywords: hiv-1 viral spike, molecular motion, protein architecture, receptor-triggered entry, type 1 fusion protein, cell membrane, disulfide bond, glycoprotein, host-virus interaction, immune response, viral protein
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 8
• Total formula weight: 222997.06

Authors

Pancera, M.,Majeed, S.,Ban, Y.A.,Chen, L.,Huang, C.C.,Kong, L.,Kwon, Y.D.,Stuckey, J.,Zhou, T.,Robinson, J.E.,Schief, W.R.,Sodroski, J.,Wyatt, R.,Kwong, P.D. (deposition date: 2009-09-18, release date: 2009-12-29, Last modification date: 2023-09-06)

• Primary citation: Pancera, M.,Majeed, S.,Ban, Y.E.,Chen, L.,Huang, C.C.,Kong, L.,Kwon, Y.D.,Stuckey, J.,Zhou, T.,Robinson, J.E.,Schief, W.R.,Sodroski, J.,Wyatt, R.,Kwong, P.D.; Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.; Proc.Natl.Acad.Sci.USA, 107:1166-1171, 2010; PubMed: 20080564; DOI: 10.1073/pnas.0911004107

Experimental method

X-RAY DIFFRACTION (2.61 Å)