3JS3
Crystal structure of type I 3-dehydroquinate dehydratase (aroD) from Clostridium difficile with covalent reaction intermediate
Summary for 3JS3
Entry DOI | 10.2210/pdb3js3/pdb |
Descriptor | 3-dehydroquinate dehydratase, 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE (3 entities in total) |
Functional Keywords | type i 3-dehydroquinate dehydratase, arod, covalent reaction intermediate, amino-acid biosynthesis, aromatic amino acid biosynthesis, lyase, schiff base, structural genomics, center for structural genomics of infectious diseases, csgid |
Biological source | Clostridium difficile |
Total number of polymer chains | 4 |
Total formula weight | 117440.86 |
Authors | Minasov, G.,Light, S.H.,Shuvalova, L.,Dubrovska, I.,Winsor, J.,Peterson, S.N.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2009-09-09, release date: 2009-09-22, Last modification date: 2023-09-06) |
Primary citation | Light, S.H.,Minasov, G.,Shuvalova, L.,Duban, M.E.,Caffrey, M.,Anderson, W.F.,Lavie, A. Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates. J.Biol.Chem., 286:3531-3539, 2011 Cited by PubMed: 21087925DOI: 10.1074/jbc.M110.192831 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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