3JQ5
Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Complex of Phospholipase A2 with Octapeptide Fragment of Amyloid Beta Peptide, Asp-Ala-Glu-Phe-Arg-His-Asp-Ser at 2 A Resolution
Summary for 3JQ5
Entry DOI | 10.2210/pdb3jq5/pdb |
Related | 1MF4 3JQL |
Descriptor | Phospholipase A2 isoform 3, Amyloid Beta Peptide, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | phospholipase a2, octapeptide, amyloid beta, hydrolase, disulfide bond, lipid degradation, metal-binding, secreted |
Biological source | Naja sagittifera (Andaman cobra) More |
Cellular location | Secreted: P60045 |
Total number of polymer chains | 2 |
Total formula weight | 14146.57 |
Authors | Mirza, Z.,Vikram, G.,Singh, N.,Sinha, M.,Bhushan, A.,Sharma, S.,Srinivasan, A.,Kaur, P.,Singh, T.P. (deposition date: 2009-09-06, release date: 2009-09-29, Last modification date: 2023-11-01) |
Primary citation | Mirza, Z.,Vikram, G.,Singh, N.,Sinha, M.,Bhushan, A.,Sharma, S.,Srinivasan, A.,Kaur, P.,Singh, T.P. Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Complex of Phospholipase A2 with Octapeptide Fragment of Amyloid Beta Peptide, Asp-Ala-Glu-Phe-Arg-His-Asp-Ser at 2 A Resolution To be Published, |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
Download full validation report