3JQ5

Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Complex of Phospholipase A2 with Octapeptide Fragment of Amyloid Beta Peptide, Asp-Ala-Glu-Phe-Arg-His-Asp-Ser at 2 A Resolution

3JQ5 の概要

• エントリーDOI: 10.2210/pdb3jq5/pdb
• 関連するPDBエントリー: 1MF4 3JQL
• 分子名称: Phospholipase A2 isoform 3, Amyloid Beta Peptide, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: phospholipase a2, octapeptide, amyloid beta, hydrolase, disulfide bond, lipid degradation, metal-binding, secreted
• 由来する生物種: Naja sagittifera (Andaman cobra); 詳細
• 細胞内の位置: Secreted: P60045
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 14146.57

構造登録者

Mirza, Z.,Vikram, G.,Singh, N.,Sinha, M.,Bhushan, A.,Sharma, S.,Srinivasan, A.,Kaur, P.,Singh, T.P. (登録日: 2009-09-06, 公開日: 2009-09-29, 最終更新日: 2024-10-30)

• 主引用文献: Mirza, Z.,Vikram, G.,Singh, N.,Sinha, M.,Bhushan, A.,Sharma, S.,Srinivasan, A.,Kaur, P.,Singh, T.P.; Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Complex of Phospholipase A2 with Octapeptide Fragment of Amyloid Beta Peptide, Asp-Ala-Glu-Phe-Arg-His-Asp-Ser at 2 A Resolution; To be Published,

実験手法

X-RAY DIFFRACTION (2.03 Å)