cryo-EM structure of the full-length human NPC1 at 4.4 angstrom

Summary for 3JD8

EMDB information6640
DescriptorNiemann-Pick C1 protein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... (5 entities in total)
Functional Keywordsmembrane protein
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight147845.4
Gong, X.,Qian, H.W.,Zhou, X.H.,Wu, J.P.,Zhou, Q.,Yan, N. (deposition date: 2016-05-01, release date: 2016-06-01, Last modification date: 2019-10-09)
Primary citation
Gong, X.,Qiang, H.W.,Zhou, X.H.,Wu, J.P.,Zhou, Q.,Yan, N.
The structure of Niemann-Pick C1 protein
To Be Published,
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers76 8.4% 13.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report