Structure of Simian Immunodeficiency Virus Envelope Spikes bound with CD4 and Monoclonal Antibody 36D5

Summary for 3JCC

EMDB information6543 6538 6539 6540 6541 6542
DescriptorEnvelope glycoprotein gp120, Antibody 36D5 light chain, Antibody 36D5 heavy chain, ... (4 entities in total)
Functional Keywordscryoelectron tomography, immunology, aids, hiv, viral protein-immune system complex, viral protein/immune system
Biological sourceSimian immunodeficiency virus (SIV)
Cellular locationCell membrane ; Single-pass type I membrane protein  P01730
Total number of polymer chains6
Total molecular weight217240.76
Hu, G.,Liu, J.,Roux, K.,Taylor, K.A. (deposition date: 2015-11-25, release date: 2017-05-10, Last modification date: 2017-08-30)
Primary citation
Hu, G.,Liu, J.,Roux, K.H.,Taylor, K.A.
Structure of Simian Immunodeficiency Virus Envelope Spikes Bound with CD4 and Monoclonal Antibody 36D5.
J. Virol., 91:-, 2017
PubMed: 28539445 (PDB entries with the same primary citation)
DOI: 10.1128/JVI.00134-17
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers02.4%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures