3JC5

Structure of the eukaryotic replicative CMG helicase and pumpjack motion

Summary for 3JC5

Entry DOI	10.2210/pdb3jc5/pdb
Related	3JC6 3JC7
EMDB information	6534 6535 6536
Descriptor	DNA replication licensing factor MCM2, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF3, ... (11 entities in total)
Functional Keywords	cmg helicase, cryo-em, hydrolase
Biological source	Saccharomyces cerevisiae (yeast) More
Total number of polymer chains	11
Total formula weight	785757.88
Authors	Li, H.,Bai, L.,Yuan, Z.,Sun, J.,Georgescu, R.E.,Liu, J.,O'Donnell, M.E. (deposition date: 2015-11-24, release date: 2016-02-10, Last modification date: 2018-07-18)
Primary citation	Yuan, Z.,Bai, L.,Sun, J.,Georgescu, R.,Liu, J.,O'Donnell, M.E.,Li, H. Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation. Nat.Struct.Mol.Biol., 23:217-224, 2016 Cited by PubMed: 26854665 DOI: 10.1038/nsmb.3170 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.7 Å)

Structure validation