3JBH

TWO HEAVY MEROMYOSIN INTERACTING-HEADS MOTIFS FLEXIBLE DOCKED INTO TARANTULA THICK FILAMENT 3D-MAP ALLOWS IN DEPTH STUDY OF INTRA- AND INTERMOLECULAR INTERACTIONS

3JBH の概要

• エントリーDOI: 10.2210/pdb3jbh/pdb
• 関連するPDBエントリー: 3DTP
• EMDBエントリー: 1950
• 分子名称: MYOSIN 2 HEAVY CHAIN STRIATED MUSCLE, MYOSIN 2 ESSENTIAL LIGHT CHAIN STRIATED MUSCLE, MYOSIN 2 REGULATORY LIGHT CHAIN STRIATED MUSCLE (3 entities in total)
• 機能のキーワード: myosin interacting-heads motif, cryo-em, thick filament, flexible docking, single particle reconstruction, iterative helical real space reconstruction (ihrsr), inter- and intramolecular interactions, myosin regulation, super-relaxation, striated muscle, tarantula, contractile protein
• 由来する生物種: Aphonopelma (tarantula); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 1055858.66

構造登録者

Alamo, L.,Qi, D.,Wriggers, W.,Pinto, A.,Zhu, J.,Bilbao, A.,Gillilan, R.E.,Hu, S.,Padron, R. (登録日: 2015-09-01, 公開日: 2016-03-09, 最終更新日: 2024-02-21)

• 主引用文献: Alamo, L.,Qi, D.,Wriggers, W.,Pinto, A.,Zhu, J.,Bilbao, A.,Gillilan, R.E.,Hu, S.,Padron, R.; Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis.; J. Mol. Biol., 428:1142-1164, 2016; PubMed: 26851071; DOI: 10.1016/j.jmb.2016.01.027

実験手法

ELECTRON MICROSCOPY (20 Å)