3IXY

The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53

3IXY の概要

• エントリーDOI: 10.2210/pdb3ixy/pdb
• EMDBエントリー: 5102
• 分子名称: Envelope protein E, Peptide pr, E53 Fab Fragment (chain H), ... (4 entities in total)
• 機能のキーワード: dengue virus, denv, immature, fusion loop, fab, e53, atp-binding, envelope protein, helicase, hydrolase, membrane, nucleotide-binding, rna replication, transmembrane, virion, capsid protein, cleavage on pair of basic residues, core protein, endoplasmic reticulum, glycoprotein, secreted, virus
• 由来する生物種: Dengue virus 2; 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 253935.05

構造登録者

Cherrier, M.V.,Kaufmann, B.,Nybakken, G.E.,Lok, S.M.,Warren, J.T.,Nelson, C.A.,Kostyuchenko, V.A.,Holdaway, H.A.,Chipman, P.R.,Kuhn, R.J.,Diamond, M.S.,Rossmann, M.G.,Fremont, D.H. (登録日: 2009-02-26, 公開日: 2009-10-27, 最終更新日: 2024-02-21)

• 主引用文献: Cherrier, M.V.,Kaufmann, B.,Nybakken, G.E.,Lok, S.M.,Warren, J.T.,Chen, B.R.,Nelson, C.A.,Kostyuchenko, V.A.,Holdaway, H.A.,Chipman, P.R.,Kuhn, R.J.,Diamond, M.S.,Rossmann, M.G.,Fremont, D.H.; Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody; Embo J., 28:3269-3276, 2009; PubMed: 19713934; DOI: 10.1038/emboj.2009.245

実験手法

ELECTRON MICROSCOPY (23 Å)