Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3IWV

Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP)

Summary for 3IWV
Entry DOI10.2210/pdb3iwv/pdb
Related2H1X 2H6U 3IWU
Descriptor5-hydroxyisourate hydrolase (2 entities in total)
Functional Keywordstransthyretin, molecular evolution, uric acid degradation, thyroid hormones, hydrolase, peroxisome, purine metabolism
Biological sourceDanio rerio (Zebrafish)
Total number of polymer chains4
Total formula weight61766.62
Authors
Cendron, L.,Ramazzina, I.,Berni, R.,Percudani, R.,Zanotti, G. (deposition date: 2009-09-03, release date: 2010-09-01, Last modification date: 2023-11-01)
Primary citationCendron, L.,Ramazzina, I.,Percudani, R.,Rasore, C.,Zanotti, G.,Berni, R.
Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409:504-512, 2011
Cited by
PubMed: 21515285
DOI: 10.1016/j.jmb.2011.04.022
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.68 Å)
Structure validation

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon