3IVS
Homocitrate Synthase Lys4
Summary for 3IVS
| Entry DOI | 10.2210/pdb3ivs/pdb |
| Related | 3IVT 3IVU |
| Descriptor | Homocitrate synthase, mitochondrial, COBALT (II) ION, MAGNESIUM ION, ... (4 entities in total) |
| Functional Keywords | tim barrel, metalloprotein, transferase, claisen condensation, amino-acid biosynthesis, lysine biosynthesis, mitochondrion, transit peptide |
| Biological source | Schizosaccharomyces pombe (Fission yeast) |
| Cellular location | Mitochondrion : Q9Y823 |
| Total number of polymer chains | 2 |
| Total formula weight | 94520.56 |
| Authors | Bulfer, S.L.,Scott, E.M.,Couture, J.-F.,Pillus, L.,Trievel, R.C. (deposition date: 2009-09-01, release date: 2009-09-22, Last modification date: 2024-04-03) |
| Primary citation | Bulfer, S.L.,Scott, E.M.,Couture, J.F.,Pillus, L.,Trievel, R.C. Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. J.Biol.Chem., 284:35769-35780, 2009 Cited by PubMed: 19776021DOI: 10.1074/jbc.M109.046821 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
Download full validation report
