3IUC
Crystal structure of the human 70kDa heat shock protein 5 (BiP/GRP78) ATPase domain in complex with ADP
Summary for 3IUC
Entry DOI | 10.2210/pdb3iuc/pdb |
Descriptor | Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa), ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | helix, structural genomics, structural genomics consortium, sgc, atp-binding, nucleotide-binding, stress response, chaperone |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 91422.62 |
Authors | Wisniewska, M.,Karlberg, T.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kallas, A.,Kotyenova, T.,Kotzch, A.,Kraulis, P.,Markova, N.,Moche, M.,Nielsen, T.K.,Nordlund, P.,Nyman, T.,Persson, C.,Roos, A.,Schutz, P.,Siponen, M.I.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Wahlberg, E.,Weigelt, J.,Welin, M.,Schuler, H.,Structural Genomics Consortium (SGC) (deposition date: 2009-08-31, release date: 2009-09-22, Last modification date: 2023-11-01) |
Primary citation | Wisniewska, M.,Karlberg, T.,Lehtio, L.,Johansson, I.,Kotenyova, T.,Moche, M.,Schuler, H. Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78 Plos One, 5:e8625-e8625, 2010 Cited by PubMed: 20072699DOI: 10.1371/journal.pone.0008625 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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