3IT6

The Crystal Structure of Ornithine Acetyltransferase complexed with Ornithine from Mycobacterium tuberculosis (Rv1653) at 2.4 A

Summary for 3IT6

• Entry DOI: 10.2210/pdb3it6/pdb
• Descriptor: Arginine biosynthesis bifunctional protein argJ alpha chain, Arginine biosynthesis bifunctional protein argJ beta chain, L-ornithine, ... (4 entities in total)
• Functional Keywords: mycobacterium tuberculosis, ornithine acetyltransferase, structural genomics, psi, protein structure initiative, tb structural genomics consortium (tbsgc), acyltransferase, amino-acid biosynthesis, arginine biosynthesis, multifunctional enzyme, transferase
• Biological source: Mycobacterium tuberculosis; More
• Cellular location: Cytoplasm (Probable): P63571 P63571
• Total number of polymer chains: 4
• Total formula weight: 82604.68

Authors

Sankaranarayanan, R.,Cherney, M.M.,Garen, C.,Garen, G.,Yuan, M.,James, M.N.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2009-08-27, release date: 2010-03-02, Last modification date: 2023-09-06)

• Primary citation: Sankaranarayanan, R.,Cherney, M.M.,Garen, C.,Garen, G.,Niu, C.,Yuan, M.,James, M.N.; The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor.; J.Mol.Biol., 397:979-990, 2010; PubMed: 20184895; DOI: 10.1016/j.jmb.2010.02.018

Experimental method

X-RAY DIFFRACTION (2.4 Å)