3IT4

The Crystal Structure of Ornithine Acetyltransferase from Mycobacterium tuberculosis (Rv1653) at 1.7 A

Summary for 3IT4

Entry DOI	10.2210/pdb3it4/pdb
Descriptor	Arginine biosynthesis bifunctional protein argJ alpha chain, Arginine biosynthesis bifunctional protein argJ beta chain, GLYCEROL, ... (6 entities in total)
Functional Keywords	mycobacterium tuberculosis, ornithine acetyltransferase, structural genomics, tb structural genomics consortium (tbsgc), acyltransferase, amino-acid biosynthesis, arginine biosynthesis, cytoplasm, multifunctional enzyme, transferase
Biological source	Mycobacterium tuberculosis More
Cellular location	Cytoplasm (Probable): P63571 P63571
Total number of polymer chains	4
Total formula weight	82856.85
Authors	Sankaranarayanan, R.,Cherney, M.M.,Garen, C.,Garen, G.,Yuan, M.,James, M.N.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2009-08-27, release date: 2010-03-02, Last modification date: 2023-09-06)
Primary citation	Sankaranarayanan, R.,Cherney, M.M.,Garen, C.,Garen, G.,Niu, C.,Yuan, M.,James, M.N. The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor. J.Mol.Biol., 397:979-990, 2010 Cited by PubMed: 20184895 DOI: 10.1016/j.jmb.2010.02.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation