3IRR
Crystal Structure of a Z-Z junction (with HEPES intercalating)
Summary for 3IRR
Entry DOI | 10.2210/pdb3irr/pdb |
Related | 1QBJ 3IRQ |
Descriptor | Double-stranded RNA-specific adenosine deaminase, DNA (5'-D(*G*TP*CP*GP*CP*GP*CP*GP*TP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*A*CP*CP*GP*CP*GP*CP*GP*AP*CP*GP*CP*GP*CP*G)-3'), ... (5 entities in total) |
Functional Keywords | z-dna, adar1, rna editing, innate immunity, dna junction, z domain, intercalation, alternative promoter usage, alternative splicing, cytoplasm, disease mutation, dna-binding, hydrolase, isopeptide bond, metal-binding, mrna processing, nucleus, phosphoprotein, polymorphism, rna-binding, rna-mediated gene silencing, ubl conjugation, zinc, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P55265 |
Total number of polymer chains | 6 |
Total formula weight | 38912.56 |
Authors | Athanasiadis, A.,de Rosa, M. (deposition date: 2009-08-24, release date: 2010-05-19, Last modification date: 2023-09-06) |
Primary citation | de Rosa, M.,de Sanctis, D.,Rosario, A.L.,Archer, M.,Rich, A.,Athanasiadis, A.,Carrondo, M.A. Crystal structure of a junction between two Z-DNA helices. Proc.Natl.Acad.Sci.USA, 107:9088-9092, 2010 Cited by PubMed: 20439751DOI: 10.1073/pnas.1003182107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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