3IRQ

Crystal structure of a Z-Z junction

3IRQ の概要

• エントリーDOI: 10.2210/pdb3irq/pdb
• 関連するPDBエントリー: 1QBJ 3IRR
• 分子名称: Double-stranded RNA-specific adenosine deaminase, DNA (5'-D(*GP*TP*CP*GP*CP*GP*CP*GP*TP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*AP*CP*CP*GP*CP*GP*CP*GP*AP*CP*GP*CP*GP*CP*G)-3'), ... (4 entities in total)
• 機能のキーワード: z-dna, adar1, rna editing, innate immunity, dna junction, z domain, alternative promoter usage, alternative splicing, cytoplasm, disease mutation, dna-binding, hydrolase, isopeptide bond, metal-binding, mrna processing, nucleus, phosphoprotein, polymorphism, rna-binding, rna-mediated gene silencing, ubl conjugation, zinc, hydrolase-dna complex, hydrolase/dna
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P55265
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 38674.26

構造登録者

Athanasiadis, A.,de Rosa, M. (登録日: 2009-08-24, 公開日: 2010-05-19, 最終更新日: 2023-09-06)

• 主引用文献: de Rosa, M.,de Sanctis, D.,Rosario, A.L.,Archer, M.,Rich, A.,Athanasiadis, A.,Carrondo, M.A.; Crystal structure of a junction between two Z-DNA helices.; Proc.Natl.Acad.Sci.USA, 107:9088-9092, 2010; PubMed: 20439751; DOI: 10.1073/pnas.1003182107

実験手法

X-RAY DIFFRACTION (2.8 Å)