3IKE

Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytosine

3IKE の概要

• エントリーDOI: 10.2210/pdb3ike/pdb
• 関連するPDBエントリー: 3F0D 3F0E 3F0F 3F0G 3IEQ 3IEW 3IKF
• 分子名称: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 6-AMINOPYRIMIDIN-2(1H)-ONE, ... (6 entities in total)
• 機能のキーワード: niaid, ssgcid, seattle structural genomics center for infectious disease, fragment, isoprene biosynthesis, lyase, metal-binding
• 由来する生物種: Burkholderia pseudomallei (Pseudomonas pseudomallei)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 53076.93

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2009-08-05, 公開日: 2009-08-18, 最終更新日: 2023-09-06)

• 主引用文献: Begley, D.W.,Hartley, R.C.,Davies, D.R.,Edwards, T.E.,Leonard, J.T.,Abendroth, J.,Burris, C.A.,Bhandari, J.,Myler, P.J.,Staker, B.L.,Stewart, L.J.; Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.; J Struct Funct Genomics, 12:63-76, 2011; PubMed: 21359640; DOI: 10.1007/s10969-011-9102-6

実験手法

X-RAY DIFFRACTION (2.3 Å)