3IJE

Crystal structure of the complete integrin alhaVbeta3 ectodomain plus an Alpha/beta transmembrane fragment

3IJE の概要

• エントリーDOI: 10.2210/pdb3ije/pdb
• 分子名称: Integrin alpha-V, Integrin beta-3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: integrin structure, activation, egf domains, flim, cell signaling, cell adhesion, cleavage on pair of basic residues, disulfide bond, glycoprotein, host-virus interaction, integrin, membrane, receptor, transmembrane, disease mutation, phosphoprotein, protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 190868.92

構造登録者

Xiong, J.-P.,Mahalingham, B.,Rui, X.,Hyman, B.T.,Goodman, S.L.,Arnaout, M.A. (登録日: 2009-08-04, 公開日: 2009-09-29, 最終更新日: 2023-09-06)

• 主引用文献: Xiong, J.P.,Mahalingham, B.,Alonso, J.L.,Borrelli, L.A.,Rui, X.,Anand, S.,Hyman, B.T.,Rysiok, T.,Muller-Pompalla, D.,Goodman, S.L.,Arnaout, M.A.; Crystal structure of the complete integrin alphaVbeta3 ectodomain plus an alpha/beta transmembrane fragment.; J.Cell Biol., 186:589-600, 2009; PubMed: 19704023; DOI: 10.1083/jcb.200905085

実験手法

X-RAY DIFFRACTION (2.9 Å)