3IIA
Crystal structure of apo (91-244) RIa subunit of cAMP-dependent protein kinase
Summary for 3IIA
Entry DOI | 10.2210/pdb3iia/pdb |
Related | 1NE4 1NE6 1RGS 1RL3 3FHI |
Descriptor | cAMP-dependent protein kinase type I-alpha regulatory subunit, GLYCEROL (3 entities in total) |
Functional Keywords | protein kinase a, cyclic amp, ria subunit, camp, camp-binding, disulfide bond, nucleotide-binding, phosphoprotein, transferase |
Biological source | Bos taurus (bovine) |
Cellular location | Cell membrane : P00514 |
Total number of polymer chains | 1 |
Total formula weight | 17431.66 |
Authors | Sjoberg, T.J.,Kim, C.,Kornev, A.P.,Taylor, S.S. (deposition date: 2009-07-31, release date: 2010-08-11, Last modification date: 2023-09-06) |
Primary citation | Badireddy, S.,Yunfeng, G.,Ritchie, M.,Akamine, P.,Wu, J.,Kim, C.W.,Taylor, S.S.,Qingsong, L.,Swaminathan, K.,Anand, G.S. Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design. Mol.Cell Proteomics, 10:M110.004390-M110.004390, 2011 Cited by PubMed: 21081668DOI: 10.1074/mcp.M110.004390 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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