3IHG

Crystal structure of a ternary complex of aklavinone-11 hydroxylase with FAD and aklavinone

Summary for 3IHG

Entry DOI	10.2210/pdb3ihg/pdb
Descriptor	RdmE, FLAVIN-ADENINE DINUCLEOTIDE, methyl (1R,2R,4S)-2-ethyl-2,4,5,7-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate, ... (5 entities in total)
Functional Keywords	flavoenzyme, anthracycline, polyketide biosynthesis, merohedral twinning, enzyme mechanism, hydroxylase, flavoprotein, oxidoreductase
Biological source	Streptomyces purpurascens
Total number of polymer chains	3
Total formula weight	177830.59
Authors	Lindqvist, Y.,Koskiniemi, H.,Jansson, A.,Sandalova, T.,Schneider, G. (deposition date: 2009-07-30, release date: 2009-09-29, Last modification date: 2024-02-21)
Primary citation	Lindqvist, Y.,Koskiniemi, H.,Jansson, A.,Sandalova, T.,Schnell, R.,Liu, Z.,Mantsala, P.,Niemi, J.,Schneider, G. Structural basis for substrate recognition and specificity in aklavinone-11-hydroxylase from rhodomycin biosynthesis. J.Mol.Biol., 393:966-977, 2009 Cited by PubMed: 19744497 DOI: 10.1016/j.jmb.2009.09.003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.49 Å)

Structure validation