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3IFW

Crystal structure of the S18Y variant of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester.

Summary for 3IFW
Entry DOI10.2210/pdb3ifw/pdb
Related2ETL
DescriptorUbiquitin carboxyl-terminal hydrolase isozyme L1, Ubiquitin, METHYL 4-AMINOBUTANOATE, ... (4 entities in total)
Functional Keywordsenzyme-suicide substrate complex, cytoplasm, disease mutation, glycoprotein, hydrolase, ligase, oxidation, polymorphism, protease, thiol protease, ubl conjugation pathway, isopeptide bond, nucleus, phosphoprotein, ubl conjugation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm: P09936
Total number of polymer chains2
Total formula weight33979.82
Authors
Das, C.,Boudreaux, D.,Maiti, T. (deposition date: 2009-07-26, release date: 2010-06-16, Last modification date: 2023-11-15)
Primary citationBoudreaux, D.A.,Maiti, T.K.,Davies, C.W.,Das, C.
Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation.
Proc.Natl.Acad.Sci.USA, 107:9117-9122, 2010
Cited by
PubMed: 20439756
DOI: 10.1073/pnas.0910870107
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

217705

數據於2024-03-27公開中

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