3IF7

Structure of Calmodulin complexed with its first endogenous inhibitor, sphingosylphosphorylcholine

3IF7 の概要

• エントリーDOI: 10.2210/pdb3if7/pdb
• 分子名称: Calmodulin, CALCIUM ION, 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium, ... (4 entities in total)
• 機能のキーワード: ef-hand, phospholipid, calcium binding protein, isopeptide bond, methylation, phosphoprotein
• 由来する生物種: Bos taurus (Bovine)
• 細胞内の位置: Cytoplasm: P62157
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18744.17

構造登録者

Kovacs, E.,Harmat, V.,Toth, J.,Vertessy, B.G.,Modos, K.,Kardos, J.,Liliom, K. (登録日: 2009-07-24, 公開日: 2010-06-30, 最終更新日: 2023-11-01)

• 主引用文献: Kovacs, E.,Harmat, V.,Toth, J.,Vertessy, B.G.,Modos, K.,Kardos, J.,Liliom, K.; Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid-protein interactions; Faseb J., 24:3829-3839, 2010; PubMed: 20522785; DOI: 10.1096/fj.10-155614

実験手法

X-RAY DIFFRACTION (1.6 Å)