3IDX
Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C222
Summary for 3IDX
Entry DOI | 10.2210/pdb3idx/pdb |
Related | 3IDY |
Descriptor | HIV-1 HxBc2 gp120 core, Fab b13 heavy chain, Fab b13 light chain, ... (8 entities in total) |
Functional Keywords | hiv-1, antibody, gp120, b13, envelope glycan protein, cd4-binding site, aids, apoptosis, cell membrane, cleavage on pair of basic residues, disulfide bond, envelope protein, fusion protein, host-virus interaction, membrane, transmembrane, viral immunoevasion, virion, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 3 |
Total formula weight | 88069.21 |
Authors | Chen, L.,Kwon, Y.D.,Zhou, T.,Wu, X.,O'Dell, S.,Cavacini, L.,Hessell, A.J.,Pancera, M.,Tang, M.,Xu, L.,Yang, Z.Y.,Zhang, M.Y.,Arthos, J.,Burton, D.R.,Dimitrov, D.S.,Nabel, G.J.,Posner, M.,Sodroski, J.,Wyatt, R.,Mascola, J.R.,Kwong, P.D. (deposition date: 2009-07-22, release date: 2009-11-17, Last modification date: 2023-09-06) |
Primary citation | Chen, L.,Do Kwon, Y.,Zhou, T.,Wu, X.,O'Dell, S.,Cavacini, L.,Hessell, A.J.,Pancera, M.,Tang, M.,Xu, L.,Yang, Z.Y.,Zhang, M.Y.,Arthos, J.,Burton, D.R.,Dimitrov, D.S.,Nabel, G.J.,Posner, M.R.,Sodroski, J.,Wyatt, R.,Mascola, J.R.,Kwong, P.D. Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science, 326:1123-1127, 2009 Cited by PubMed: 19965434DOI: 10.1126/science.1175868 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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