3IC0

Crystal Structure of liganded hemoglobin in complex with a potent antisickling agent, INN-298

3IC0 の概要

• エントリーDOI: 10.2210/pdb3ic0/pdb
• 関連するPDBエントリー: 3IC2
• 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... (7 entities in total)
• 機能のキーワード: heme protein, hemoglobin, antisickling agents, acetylation, disease mutation, glycation, glycoprotein, heme, iron, metal-binding, oxygen transport, phosphoprotein, polymorphism, transport, hypotensive agent, pyruvate, s-nitrosylation, vasoactive
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 65784.27

構造登録者

Safo, M.K.,Musayev, F.N.,Gandhi, A.K.,Jorge, P. (登録日: 2009-07-17, 公開日: 2009-07-28, 最終更新日: 2023-09-06)

• 主引用文献: Osheiza, A.,Mohini, G.,Ijoema, N.,Amit, K.G.,Faik, N.M.,Richmond, D.-D.,Toshio, A.,Martin, K.S.; Structural and in Vitro Chracterization of Pridyl Derivatives of Benzaldehydes: Highly Potent Antisickling Agents; To be Published,

実験手法

X-RAY DIFFRACTION (1.8 Å)