3IBA
Crystal structure of the complex of Trypanosoma cruzi farnesyl diphosphate synthase with zoledronate, IPP and Mg2+
Summary for 3IBA
| Entry DOI | 10.2210/pdb3iba/pdb |
| Related | 1YHK 1YHL 1YKM 3ICK 3ICM 3ICN 3ICZ 3ID0 |
| Descriptor | Farnesyl pyrophosphate synthase, MAGNESIUM ION, ZOLEDRONIC ACID, ... (6 entities in total) |
| Functional Keywords | fpps, trypanosoma cruzi, bisphosphonate, isopentenyl pyrophosphate, chagas disease, isoprene biosynthesis, transferase |
| Biological source | Trypanosoma cruzi |
| Total number of polymer chains | 1 |
| Total formula weight | 41912.48 |
| Authors | Amzel, L.M.,Huang, C.H.,Gabelli, S.B.,Oldfield, E. (deposition date: 2009-07-15, release date: 2010-02-09, Last modification date: 2024-02-21) |
| Primary citation | Huang, C.H.,Gabelli, S.B.,Oldfield, E.,Amzel, L.M. Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer. Proteins, 78:888-899, 2010 Cited by PubMed: 19876942DOI: 10.1002/prot.22614 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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