3IAR

The crystal structure of human adenosine deaminase

3IAR の概要

• エントリーDOI: 10.2210/pdb3iar/pdb
• 関連するPDBエントリー: 1KRM
• 分子名称: Adenosine deaminase, (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, NICKEL (II) ION, ... (6 entities in total)
• 機能のキーワード: deaminase, adenosine deaminase, adenosine, purine metabolism, structural genomics, structural genomics consortium, sgc, disease mutation, hereditary hemolytic anemia, hydrolase, nucleotide metabolism, scid
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane; Peripheral membrane protein; Extracellular side: P00813
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41908.03

構造登録者

Ugochukwu, E.,Zhang, Y.,Hapka, E.,Yue, W.W.,Bray, J.E.,Muniz, J.,Burgess-Brown, N.,Chaikuad, A.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Kavanagh, K.L.,Oppermann, U.,Structural Genomics Consortium (SGC) (登録日: 2009-07-14, 公開日: 2009-08-11, 最終更新日: 2023-09-06)

• 主引用文献: Ugochukwu, E.,Zhang, Y.,Hapka, E.,Yue, W.W.,Bray, J.E.,Muniz, J.,Burgess-Brown, N.,Chaikuad, A.,Kavanagh, K.L.,Oppermann, U.; The crystal structure of human adenosine deaminase; To be Published,

実験手法

X-RAY DIFFRACTION (1.52 Å)