3IAF

Structure of benzaldehyde lyase A28S mutant with monomethyl benzoylphosphonate

3IAF の概要

• エントリーDOI: 10.2210/pdb3iaf/pdb
• 関連するPDBエントリー: 3IAE
• 分子名称: Benzaldehyde lyase, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: phosphoserine, covalent sidechain adduct, lyase
• 由来する生物種: Pseudomonas fluorescens
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 241694.60

構造登録者

Brandt, G.S.,Petsko, G.A.,Ringe, D.,McLeish, M.J. (登録日: 2009-07-13, 公開日: 2010-03-02, 最終更新日: 2023-09-06)

• 主引用文献: Brandt, G.S.,Kneen, M.M.,Petsko, G.A.,Ringe, D.,McLeish, M.J.; Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition.; J.Am.Chem.Soc., 132:438-439, 2010; PubMed: 20030408; DOI: 10.1021/ja907064w

実験手法

X-RAY DIFFRACTION (2.8 Å)