3I8P

Crystal structure of E. coli FabF(C163A) in complex with Platensimycin A1

3I8P の概要

• エントリーDOI: 10.2210/pdb3i8p/pdb
• 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Platensimycin A1 (3 entities in total)
• 機能のキーワード: fabf, kasii, platensimycin a1, platensimycin, acyltransferase, fatty acid biosynthesis, lipid synthesis, transferase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45060.69

構造登録者

Soisson, S.M.,Parthsarathy, G. (登録日: 2009-07-09, 公開日: 2010-07-28, 最終更新日: 2023-09-06)

• 主引用文献: Singh, S.B.,Ondeyka, J.G.,Herath, K.B.,Zhang, C.,Jayasuriya, H.,Zink, D.L.,Parthasarathy, G.,Becker, J.W.,Wang, J.,Soisson, S.M.; Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.; Bioorg.Med.Chem.Lett., 19:4756-4759, 2009; PubMed: 19581087; DOI: 10.1016/j.bmcl.2009.06.061

実験手法

X-RAY DIFFRACTION (1.9 Å)