3I8D

The Pairing Geometry of the Hydrophobic Thymine Analog 2,4-Difluorotoluene in Duplex DNA as Analyzed by X-ray Crystallography

3I8D の概要

• エントリーDOI: 10.2210/pdb3i8d/pdb
• 分子名称: Ribonuclease H, 5'-D(*CP*GP*CP*GP*AP*AP*TP*(DFT)P*CP*GP*CP*G)-3', GLYCEROL, ... (4 entities in total)
• 機能のキーワード: rnase-h, rnase-h dna-complex, 2, 4-difluorotoluene, thymine isostere, hydrophobic base, endonuclease, hydrolase, magnesium, manganese, metal-binding, nuclease, hydrolase-dna complex, hydrolase/dna
• 由来する生物種: Bacillus halodurans
• 細胞内の位置: Cytoplasm : Q9KEI9
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 38185.58

構造登録者

Egli, M.,Pallan, P.S. (登録日: 2009-07-09, 公開日: 2009-09-01, 最終更新日: 2023-09-06)

• 主引用文献: Pallan, P.S.,Egli, M.; Pairing geometry of the hydrophobic thymine analogue 2,4-difluorotoluene in duplex DNA as analyzed by X-ray crystallography.; J.Am.Chem.Soc., 131:12548-12549, 2009; PubMed: 19685868; DOI: 10.1021/ja905739j

実験手法

X-RAY DIFFRACTION (1.61 Å)