3I7S

Dihydrodipicolinate synthase mutant - K161A - with the substrate pyruvate bound in the active site.

Summary for 3I7S

• Entry DOI: 10.2210/pdb3i7s/pdb
• Related: 3I7Q 3I7R
• Descriptor: Dihydrodipicolinate synthase, GLYCEROL, POTASSIUM ION, ... (6 entities in total)
• Functional Keywords: dihydrodipicolinate synthyase, lysine biosynthesis, amino-acid biosynthesis, diaminopimelate biosynthesis, lyase, schiff base
• Biological source: Escherichia coli K-12
• Cellular location: Cytoplasm: P0A6L2
• Total number of polymer chains: 2
• Total formula weight: 64098.27

Authors

Dobson, R.C.J.,Jameson, G.B.,Gerrard, J.A.,Soares da Costa, T.P. (deposition date: 2009-07-08, release date: 2010-04-14, Last modification date: 2023-11-15)

• Primary citation: Soares da Costa, T.P.,Muscroft-Taylor, A.C.,Dobson, R.C.,Devenish, S.R.,Jameson, G.B.,Gerrard, J.A.; How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?; Biochimie, 92:837-845, 2010; PubMed: 20353808; DOI: 10.1016/j.biochi.2010.03.004

Experimental method

X-RAY DIFFRACTION (2.3 Å)