3I79

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1)

Summary for 3I79

Entry DOI	10.2210/pdb3i79/pdb
Related	3I7B 3I7C 3MWU 3N51 3NCG
Descriptor	Calmodulin-domain protein kinase 1, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	protein kinase, calmodulin, ef hand, bumped kinase inhibitor, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, structural genomics, medical structural genomics of pathogenic protozoa, msgpp, transferase
Biological source	Toxoplasma gondii
Total number of polymer chains	1
Total formula weight	55288.98
Authors	Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (deposition date: 2009-07-08, release date: 2009-08-11, Last modification date: 2024-02-21)
Primary citation	Ojo, K.K.,Larson, E.T.,Keyloun, K.R.,Castaneda, L.J.,Derocher, A.E.,Inampudi, K.K.,Kim, J.E.,Arakaki, T.L.,Murphy, R.C.,Zhang, L.,Napuli, A.J.,Maly, D.J.,Verlinde, C.L.,Buckner, F.S.,Parsons, M.,Hol, W.G.,Merritt, E.A.,Van Voorhis, W.C. Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat.Struct.Mol.Biol., 17:602-607, 2010 Cited by PubMed: 20436472 DOI: 10.1038/nsmb.1818 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation