3I79

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1)

3I79 の概要

• エントリーDOI: 10.2210/pdb3i79/pdb
• 関連するPDBエントリー: 3I7B 3I7C 3MWU 3N51 3NCG
• 分子名称: Calmodulin-domain protein kinase 1, 1,2-ETHANEDIOL (3 entities in total)
• 機能のキーワード: protein kinase, calmodulin, ef hand, bumped kinase inhibitor, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, structural genomics, medical structural genomics of pathogenic protozoa, msgpp, transferase
• 由来する生物種: Toxoplasma gondii
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 55288.98

構造登録者

Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (登録日: 2009-07-08, 公開日: 2009-08-11, 最終更新日: 2024-02-21)

• 主引用文献: Ojo, K.K.,Larson, E.T.,Keyloun, K.R.,Castaneda, L.J.,Derocher, A.E.,Inampudi, K.K.,Kim, J.E.,Arakaki, T.L.,Murphy, R.C.,Zhang, L.,Napuli, A.J.,Maly, D.J.,Verlinde, C.L.,Buckner, F.S.,Parsons, M.,Hol, W.G.,Merritt, E.A.,Van Voorhis, W.C.; Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors.; Nat.Struct.Mol.Biol., 17:602-607, 2010; PubMed: 20436472; DOI: 10.1038/nsmb.1818

実験手法

X-RAY DIFFRACTION (2.04 Å)