3I59

Crystal structure of MtbCRP in complex with N6-cAMP

3I59 の概要

• エントリーDOI: 10.2210/pdb3i59/pdb
• 関連するPDBエントリー: 3I54
• 分子名称: Transcriptional regulator, Crp/Fnr family, (2R)-N6-(1-Methyl-2-phenylethyl)adenosine-3',5'-cyclic monophosphate, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: mycobacterium tuberculosis, camp receptor protein, crp, allosteric mechanism, dna binding, inhibition, n6-camp, structural genomics, tb structural genomics consortium, tbsgc, dna-binding, transcription, transcription regulation, dna binding protein
• 由来する生物種: Mycobacterium tuberculosis; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 56171.70

構造登録者

Reddy, M.C.,Palaninathan, S.K.,Bruning, J.B.,Thurman, C.,Smith, D.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 2009-07-03, 公開日: 2009-09-08, 最終更新日: 2023-11-22)

• 主引用文献: Reddy, M.C.,Palaninathan, S.K.,Bruning, J.B.,Thurman, C.,Smith, D.,Sacchettini, J.C.; Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein.; J.Biol.Chem., 284:36581-36591, 2009; PubMed: 19740754; DOI: 10.1074/jbc.M109.041343

実験手法

X-RAY DIFFRACTION (2.29 Å)