3I50

Crystal structure of the West Nile Virus envelope glycoprotein in complex with the E53 antibody Fab

3I50 の概要

• エントリーDOI: 10.2210/pdb3i50/pdb
• 関連するPDBエントリー: 2HG0 2I69
• 分子名称: Envelope glycoprotein, murine kappa light chain of E53 monoclonal antibody Fab, murine heavy chain (IgG3) of E53 monoclonal antibody Fab (3 entities in total)
• 機能のキーワード: antibody, fab, virus, envelope, immunoglobulin, fusion loop, disulfide bond, envelope protein, membrane, transmembrane, virion, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: West Nile virus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 89658.84

構造登録者

Nybakken, G.E.,Warren, J.T.,Chen, B.R.,Nelson, C.A.,Fremont, D.H. (登録日: 2009-07-03, 公開日: 2009-10-27, 最終更新日: 2013-09-25)

• 主引用文献: Cherrier, M.V.,Kaufmann, B.,Nybakken, G.E.,Lok, S.M.,Warren, J.T.,Chen, B.R.,Nelson, C.A.,Kostyuchenko, V.A.,Holdaway, H.A.,Chipman, P.R.,Kuhn, R.J.,Diamond, M.S.,Rossmann, M.G.,Fremont, D.H.; Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody.; Embo J., 28:3269-3276, 2009; PubMed: 19713934; DOI: 10.1038/emboj.2009.245

実験手法

X-RAY DIFFRACTION (3 Å)